Join Barb for a day-long journey through 33 feet of gastrointestinal tract and a few associated structures. This seminar covers the anatomy, physiology and pathophysiology of the GI tract from top to bottom. Beginning with the mouth and oropharynx, this lecture discusses the teeth, the tongue, the mouth, the gums, the esophagus, the stomach, and the small and large bowel. Specific clinical entities include the relationship between periodontal disease and cardiovascular disease, tonsillitis and adenoiditis and growth disturbances, esophageal varices, eosinophilic esophagitis, the many causes of cirrhosis of the liver, GERD and Barrett's esophagus, NSAID gastropathy, peptic ulcer disease and H. pylori, Celiac disease, long-term consequences of gastric surgery and gastric sleeves for weight loss, diabetes and the GI tract, the many causes of diarrhea including C. difficile, food borne pathogens and gastroenteritis, the microbiome and weight gain and loss, Crohn's disease, ulcerative colitis, appendicitis, colon cancer and rectal foreign objects. Barb discusses disease presentations as well as the newest treatment modalities for the above clinical conditions. The journey is entertaining, enlightening, and educational.